Head and neck
Vol. 45: Issue 5 - October 2025
Evaluation of the pan-immune-inflammation value in patients with Bell’s palsy
Abstract
Objectives. Pan-immune-inflammation value is an inflammation index calculated using the parameters in a complete blood count (CBC) and has gained popularity in recent years. In this study, we aimed to examine its role in Bell’s palsy. 
Methods. The study was designed as a retrospective case-control study. The study group consisted of 79 patients with Bell’s palsy. There were 158 patients in the control group. Age, gender, grade, CBC parameters and pan-immune-inflammation value were compared statistically between the groups. 
Results. Leukocyte, neutrophil, platelet and pan-immune-inflammation values were significantly higher in the Bell's palsy group than in the control group (p values: < 0.001, < 0.001, 0.03, < 0.001, respectively). There was no correlation between grade of Bell’s palsy and any study parameters. 
Conclusions. Our results support the theory that inflammation may be the main factor in pathogenesis, as the pan-immune-inflammation value is higher in patients with Bell’s palsy. Our results suggest that the cell group that plays a major role in this inflammation is neutrophils.
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Copyright (c) 2025 Società Italiana di Otorinolaringoiatria e chirurgia cervico facciale
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