Verbal task and motor responses (VTMR) in an adult hearing screening programme
The aim of this study was to test the efficacy of Verbal Tasks and Motor Responses (VTMR) speech audiometry in providing a rapid and true-to-life assessment of hearing-related problems as a single test in adult hearing screening programmes. The VTMR consists in manual execution of 5 verbal commands received by patients at different signal intensity levels and fixed masking noise; it provides a score of speech comprehension in noise. This was a prospective observational study in 916 individuals out of 1,300 volunteers (605 males, 695 females, aged 56 ± 17 years) who completed adult hearing screening. VTMR speech audiometry was performed at signal to noise (S/N) ratios of 0 dB and –10 dB. The difference between normal and hearing impaired subjects in terms of all the considered variables was statistically significant for pure-tone audiometry and VTMR testing. VTMR testing at a S/N ratio of –10 dB with a cut-off of four correctly executed tasks and was a rapid, feasible and efficient means of differentiating between normal and hearing impaired subjects. When used to screen hearing impaired subjects with participation restrictions, the sensitivity and specificity of the VTMR test rose to 90% and 62%, respectively. The VTMR test in noise could be used as a stand-alone tool when screening for impairment and self-perceived participation restriction together.
Adult hearing screening programmes are currently increasing worldwide as a result of recent concern regarding the importance of monitoring hearing, increasing awareness of hearing loss and promoting behavioural change by enhancing patient involvement 1,2. The techniques commonly used in adult hearing screening include anamnesis, visual inspection, pure-tone audiometry and self-assessment of hearing disability 3.
Pure-tone audiometry can be used to screen individuals for hearing impairment, but not for hearing disability, whereas self-assement is used to measure participation restrictions, but may not accurately assess hearing disorders or impairment 4. Furthermore, there is increasing evidence that the degree of measured peripheral hearing impairment (loss of function) may not completely reflect an individual’s real communication performance (speech comprehension) and may provide only a partial picture of the real-life experience of the activity limitations and participation restrictions (handicap) 5.
For this reason, the use of speech audiometry has been introduced in adult hearing screening in order to focus on the actual difficulties experienced by the individual with a hearing problem. These include speech communication difficulties, particularly in challenging listening situations where complications such as background noise, crowds or competing talkers are present 6. However, pure-tone audiometry and speech audiometry together are not sufficient to measure level of participation and/or participation restriction and describe only partially the social consequences of hearing loss 7.
The Verbal Tasks and Motor Responses (VTMR) speech audiometry test is an original test that was introduced in 2012 as a means of evaluating speech comprehension by soliciting the prompt execution of simple tasks (motor responses) using phonetically balanced verbal commands 8. As already reported, it allows rapid evaluation of speech comprehension by assessing the ability to simultaneously process auditory and visual information and to perform simple motor tasks with three-dimensional and standardised objects resembling familiar tools. Therefore, the VTMR test differs from other speech tests, and in particular from the vowel-consonant-vowel tests previously proposed for checking speech understanding in adult hearing screening 6. We chose to use this test because it closely reflects real-life difficulties connected with understanding commands in noise and executing tasks and therefore might provide a measure of participation restriction in hearing impaired subjects.
The aim of this study was to test the efficacy of VTMR speech audiometry in providing rapid and true-to-life assessment of hearing-related problems when used alone to screen simultaneously for both hearing loss and self perceived participation restriction in adult hearing screening programs.
Materials and methods
One thousand and three hundred volunteers (605 males, 695 females, 56 ± 17 years) were enrolled by a team of physicians and audiologists stationed in a mobile unit that travelled to 10 different locations in Milan, Italy. The event was promoted by the Public Health Department of the Municipality of Milan. The free programme of the deafness prevention campaign was advertised with flyers, posters and on the Internet. The subjects could make an appointment directly on site or by calling a free phone number. The locations were chosen in order to obtain a realistic sample of the entire urban community (city centre and suburbs, residential and industrial areas, peaceful and noisy neighbourhoods).
In accordance with American Speech-Language-Hearing Association (ASHA) guidelines 3, exclusion criteria consisted of visual identification of physical abnormality of the outer ear, otoscopic identification of ear canal abnormality, cerumen impaction, previous ear surgery or otological disease (such as middle ear pathology e.g. acute otitis media, inactive or active chronic otitis media, congenital ear abnormalities or more than two acute episodes of vertigo or persisting dizziness). Patients with a positive history of psychiatric, neurologic disorders or mild cognitive impairment were excluded.
None of the interviewed subjects had previously taken part in hearing conservation programmes or training courses aimed at managing ear diseases and reducing the risk of hearing loss.
After review of clinical history by a physicians, all volunteers were asked to complete an informative questionnaire on audiologic issues that measured their knowledge of managing and preventing ear disease and hearing loss 11. Clinical otoscopy, consisting of visual inspection of the outer ear using clinical otoscopes, was used for otological evaluation of each subject to identify any individuals requiring medical referral and to determine candidacy for adult hearing screening. The Pass/Refer criteria used were:
All subjects underwent audiological evaluation with pure-tone audiometry for the frequencies of 500, 1,000, 2,000 and 4,000 Hz using an audiometer (Amplaid A177 plus, Amplifon, Milan, Italy) with TDH-49 headphones. Ambient noise levels inside the sound-treated booth were checked four times a day to verify that they did not exceed American National Standards Institute (ANSI) levels 10. In order to comply with the ASHA guidelines, 500 Hz values have not been included in the analysis for its higher variability due to their influence on environmental noise 3. Subjects’hearing was considered normal if responses to pure-tone air-conduction stimuli lower than 25 dB HL at 1,000, 2,000 and 4,000 Hz were obtained in both ears or in the poorer ear, according to the ASHA guidelines 3.
Once the first audiological phase of evaluation had been completed, an external CD player was connected to the audiometer and the VTMR test was played through two loudspeakers placed in front and at the back of the listener (0° and 180° azimuth), at a distance of 1 m from the subject, according to ANSI S3.6-2010 11. The VTMR test CD starts with a stereo calibration tone of 1 kHz at 60 dB SPL lasting 30 seconds. The root-mean-squared (RMS) output level of the recorded voice is 60 dB SPL with a peak variation not exceeding ± 3 dB SPL.
The test consists of a set of familiar objects (a base, a hammer and a wooden structure with four sticks and five rings of different colours) and 20 lists of five simple tasks, all with the same level of motor execution difficulty, colour types and spectral frequency pattern (according to the Italian language), that are recorded on the CD with a pause of 8 seconds between each task (Fig. 1). The lists can be used randomly, since the choice of colours and objects was originally determined by a balance in the spectral frequency, and Fast Fourier analysis revealed no significant differences in intensity for each frequency in the 20 lists 8. Each correctly performed task receives a score of 20, and the results obtained with each list are tallied as a percent-correct value of 100 for each list of five verbal tasks. Hereunder, we report two of the 5-task lists:
After one training list, two lists of VTMR speech audiometry were randomly chosen and proposed to all subjects at two fixed S/N ratios: 0 dB and –10 dB. The choice of –10 dB of S/N ratio was meant to check the speech comprehension behaviour in a worse noisy environment, especially when pure tone hearing was normal.
Participation restriction questionnaires
According to the ASHA guidelines, self-assessment screening of perceived hearing handicap and communication-specific problems was carried out using the Hearing Handicap Inventory for the Elderly questionnaire, short form (HHIEsf) 12. This inventory is commonly used to investigate the area of participation, in order to assess residual participation restrictions, i.e. the problems or barriers encountered during situations of daily life in which hearing plays a role 13. It consists of 10 standardised questions including five social or situational items and five emotional response items. A response of ‘‘yes’’ is given 4 points, ‘‘sometimes’’ is given 2 points, and ‘‘no’’ is given 0 points; therefore, the HHIEsf scores range from 0 to 40. According to the HHIEsf raw score handicap range, the post-hoc probability of hearing impairment is reported to be 13% for “no handicap” (0-8), 50% in Mild-to-Moderate Handicap (10-24) and 84% for Severe Handicap (26-40) 14.
The study was approved by the Government Ethical Committee and the Health Department of Milan.
The validity of VTMR testing was assessed using the receiver operating characteristics (ROC) curve, the area under the ROC curve (AUC) and Youden’s index. Multiple logistic regression analysis was used to identify independent factors that were associated with hearing loss, combining pure-tone audiometry and VTMR testing. All statistical analyses were performed using SAS 9.2 (Cary, NC, USA); a two-sided p < 0.05 was considered significant.
Three hundred eighty-four of the 1,300 volunteers interviewed were excluded from VTMR testing since they did not meet inclusion criteria. The following statistical analysis is based on the results obtained from the 916 subjects considered eligible to perform the whole audiological evaluation. Table I shows various characteristics of the subjects tested (age, sex and profession). None had single side deafness. Subjects were divided into two categories: normal and hearing-impaired on the basis of pure-tone audiometry.
The results to the HHIEsf questionnaire are reported in Table II.
Figure 2 shows the ROC curves obtained from VTMR testing at a S/N ratio of 0 dB (dotted grey line) and –10 dB (continuous grey line). Since the AUC for a S/N ratio of –10 dB is greater, this S/N ratio is more efficient in differentiating between normal and hearing impaired subjects. As shown in the graph, four correctly executed motor responses represent the cut-off value. This threshold expressed the highest value by the Youden’s index (J) (Tab. III).
Table III shows the results of hearing impairment evaluation based on sensitivity, specificity and resulting Youden’s index, of each value of VTMR speech audiometry with a S/N ratio of –10 dB. When evaluating the self-perceived participation restrictions (HHIEsf > 24/40), the sensitivity and specificity of VTMR testing increase to 78% and 63%, respectively, at a S/N ratio of –10 dB with a cut-off of at least four correctly executed tasks. If hearing impairment and self-perceived severe participation restrictions are taken into account together, sensitivity and specificity further increased up to 90% and 62%, respectively.
Table IV shows the distribution of normal hearing and hearing-impaired subjects in relation with the number of correct answers to the VTMR test (S/N –10 dB). While all normal hearing subjects answered correctly to the VMTR test by repeating all five motor tasks, only 170 of 405 hearing impaired subjects performed it correctly. Furthermore, when considering together the results at pure-tone audiometry and HHIEsf, only 3 subjects gave 5/5 correct answers to the VTMR: two women (44 and 37 years old with a score of 26/40 and 32/40) and one man (71 years old with a score of 28/40) with asymmetrical sensorineural hearing loss. In the normal hearing group, there were only two normally hearing subjects who reported a score of HHIEsf > 24/40 (one 43-year-old man with a score of 30/40 and one 29-year-old woman with a score of 36/40): they returned a score of 5 correctly executed tasks at both S/N ratios at the VTMR testing. In the group of hearing impaired subjects with low or mild-to-moderate participation restrictions, sensitivity was 0.51 and 0.60 and specificity was 0.90 and 0.77, respectively. As reported in Table III, one or more mistakes (< 5/5) at VTMR testing (S/N –10 dB) allowed detection of subjects with hearing impairment and participation restriction (HHIEsf > 24/40) with a good sensitivity and specificity (0.90 and 0.68, respectively). The number of correctly executed motor responses at VTMR testing (S/N –10 dB) were significantly different in relation with sex, age and HHIEsf scores (p < 0.0001). Table V compares pure-tone audiometry and VTMR testing using multiple logistic regression analysis with a cut-off of 4 correctly executed motor responses. The difference between normal and hearing impaired subjects was statistically significant for all the considered variables. The results of the VTMR test were homogeneous with pure-tone audiometry, but were slightly more influenced by subjective self-perception (HHIEsf).
The absence of partecipation restrictions in normally hearing subjects was clearly recognised by VTMR, compared with the severe partecipations restrictions in hearing impaired subjects (> 24/40) (Fig. 3). The AUC for a S/N ratio of –10 dB was 0.835.
As stated in ASHA guidelines, the identification of hearing losses exceeding a predetermined screening level (e.g. 25 dB HL) by pure tone audiometry across the frequency range of 1,000 to 4,000 Hz has shown an excellent sensitivity (95-99%) and specificity (78%-99%) 15. Speech audiometry is a fundamental tool in audiological evaluation, aimed at examining the speech-processing abilities throughout the auditory system; it can also be used to crosscheck the validity of pure-tone thresholds 3. Speech tests have been proposed for adult hearing screening, but have shown widely different results depending on the protocol used; the reported sensitivity and specificity vary between 75% and 84% for the vowel-consonant-vowel 6, and 91-93% for the digit triplet speech test in noise 15,16. In our study, the sensitivity and specificity of speech comprehension in noise with VTMR test was even lower (58% and 75%) than those of other speech tests when used to screen only peripheral function. In this respect, our findings support the well known advantage of pure tone audiometry for assessment of peripheral hearing impairment 14. Nevertheless, many studies have shown that the ability to comprehend speech in challenging (e.g. noisy or reverberant) listening situations is influenced either by bottom-up peripheral auditory processes and by top-down cognitive abilities 5,17-22. However, as reported by Jerger et al., only the synthetic sentence identification (SSI) test and dichotic sentence identification (DSI) are related to cognitive abilities 23.
Difficulty in speech understanding in noisy conditions is one of the most notorious complaints of people with hearing; it is often related to self-perceived hearing disability. In the audiological diagnostic work-up, speech-in-noise tests based on sentences are widely accepted as appropriate tools for assessment of a subject’s ability to understand speech in noisy and daily-life situations 24. However, when proposed as a unique measure of hearing impairment and disability in adult hearing screening programs, the results of speech tests, such as the Synthetic Sentence Identification test, Speech Perception in Noise at an S/N ratio of +8 dB, Dichotic Sentence Identification test and degraded word recognition tasks, were sometimes unsatisfactory or insufficiently reliable, and many authors have concluded that they should have been improved 25-28. Matthews et al (1990) reported a lack of correlation between Speech Perception in Noise test and total scores on the HHIE 29.
Conversely, when we took into account a measure of severe self-perceived difficulty in comprehension of speech in noisy conditions, the VTMR test in noise at the pre-set cut-off value of 4 of 5 correctly executed tasks correlated well, with the hearing loss identified by pure tone audiometry and the self-report measure of participation restriction: sensitivity and specificity were 0.90 and 0.62, respectively. This finding might be justified by the fact that the VTMR test does not only quantify speech understanding in noise, but combines visual identification, working memory, speech comprehension and motor execution 8. The VTMR test, in fact, is more redundant than other speech tests, and therefore it might more closely resemble the difficulty and disability experienced by a hearing-impaired individual, especially in the absence of appropriate auxiliary aids and proper support for effective communication.
When attempting to demonstrate a difference in speech comprehension between normal and hearing impaired subjects, a S/N ratio of –10 dB was more effective than a S/N of 0 dB. This finding suggests that a S/N –10 dB better exploits the redundancy of information implied by the selected tasks. Further advantages of the VTMR testing at an S/N ratio of –10 dB with a cut-off of four of five correctly executed tasks are rapidity, low-cost, high specificity and feasibility, which are all useful characteristics in a screening setting.
It has been demonstrated to be a user-friendly test with a high level of redundancy, since it is based on a set of familiar objects whose function is intrinsic, e.g.: the hammer is obviously meant to hit the sticks. The results of the VTMR test are clearly understandable by subjects and may motivate them to seek audiological help. However, a limit of this study is the lack of comparison with other sentences in noise tests; the results cannot be easily transferred to a clinical diagnostic setting: in order to do that, repeatability should be established, by determining consistency over repeated measures and test-rest variability, which is not feasible in a screening setting. In our previous work, the comparison between VTMR and traditional speech test with bysillabic words was performed in quiet, showing a good correlation between the two tests 8.
Speech in noise tests using the VTMR test instructions were highly sensitive in distinguishing subjects with disabling hearing loss; the risk of false negative results was significantly reduced.
Our findings suggest that this method might be used as a stand-alone tool to simultaneously screen for impairment and participation restrictions, which are complementary and equally important aspects of any adult hearing screening programme.
Figures and tables
|Characteristics||Overall (n = 916)||Normal ≤ 25 dB HL (n = 511)||Hearing loss > 25 dB HL (n = 405)|
|Age a||55 (42; 66)||47 (34; 57)||64 (55; 71)|
|M||382 (42.1%)||166 (32.4%)||220 (54.3%)|
|F||530 (57.9%)||345 (67.6%)||185 (45.7%)|
|Housewife||87 (9.5%)||44 (8.6%)||43 (10.6%)|
|Retired||278 (30.4%)||80 (15.7%)||198 (48.9%)|
|Employee||198 (21.6%)||151 (29.6%)||46 (11.4%)|
|Student||65 (7.1%)||60 (11.7%)||5 (1.2%)|
|Workman||73 (8.0%)||48 (9.4%)||25 (6.2%)|
|Unemployed||13 (1.4%)||9 (1.9%)||4 (1.0%)|
|Teacher||41 (4.5%)||35 (6.9%)||6 (1.5%)|
|Manager/self employed||108 (11.8%)||54 (10.6%)||54 (13.3%)|
|Overall (n = 916)||Normal ≤ 25 dB HL (n = 511)||Hearing loss > 25 dB HL (n = 405)|
|HHIEsf a||6 (2;12)||4 (0;8)||8 (4;16)|
|Low b||602 (100%)||400 (66.4%)||202 (33.6%)|
|Mild-to-moderate b||260 (100%)||91 (35.0%)||169 (65.0%)|
|Severe b||38(100)||8 (21.0%)||30 (79.0%)|
|VTMR||Hearing impairment||Participations restriction||Hearing impairment and participations restriction|
|Sensitivity||Specificity||J *||Sensitivity||Specificity||J *||Sensitivity||Specificity||J *|
|VTMR||Normal ≤ 25 dB HL (n = 511)||Hearing loss > 25 dB HL (n = 405)|
|0||1 (0.2%)||54 (13.3%)|
|1||12 (2.3%)||26 (6.4%)|
|2||20 (3.9%)||32 (7.9%)|
|3||32 (6.3%)||49 (12.1%)|
|4||61 (11.9%)||74 (18.3%)|
|5||385 (75.3%)||170 (42.0%)|
|Characteristics||Pure-tone audiometry OR (95% CI)||VTMR OR (95% CI)|
|Age||0-44 45-64 65+||1 (ref) 4.9 (3.2-7.6) 26.3 (15.9-43.6)||1 (ref) 2.5 (1.7-3.7) 7.1 (4.9-10.8)|
|Sex||F M||1 (ref) 2.8 (2.0-3.9)||1 (ref) 1.5 (1.1-2.0)|
|Disability (HHIEsf)||Low Mild-to-moderate Severe||1 (ref) 3.7 (2.6-5.3) 6.6 (2.5-17.1)||1 (ref) 1.5 (1.1-2.1) 6.0 (1.5-14.0)|