A case of otoliquorrhoea secondary to immunotherapy response in head and neck cutaneous squamous cell carcinoma. When abrupt response may worry the physician| ACTA Otorhinolaryngologica Italica
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DOI: 10.14639/0392-100X-N2647
Letters to the Editor-in-Chief
Published: 2023-10-10
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A case of otoliquorrhoea secondary to immunotherapy response in head and neck cutaneous squamous cell carcinoma. When abrupt response may worry the physician

Medical Oncology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy
Otorhinolaryngology-Head and Neck Surgery Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy
Radiology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy
Medical Oncology Unit, Department of Medical & Surgical Specialties, Radiological Sciences & Public Health, University of Brescia, ASST Spedali Civili, 25123 Brescia, Italy
Radiology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy
Otorhinolaryngology–Head and Neck Surgery Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy
Neurosurgery Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy
Medical Oncology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy
cutaneous squamous cell carcinoma head and neck cerebrospinal fluid leak immunotherapy

Abstract

Dear Editor,
Extension of cutaneous squamous cell carcinoma (cSCC) to the temporal bone represents a challenging scenario associated with poor outcomes. Scarce literature data is available to guide clinicians towards the optimal management of this disease. A dedicated TNM staging is lacking, and the modified Pittsburgh classification is typically adopted. Up to 80% of cSCC arises in the head and neck (HN) area, and the ear is part of the so called “H-zone”, an area at highrisk for tumour. Invasion of temporal bone is a condition to be considered in auricular cSCC, representing the consequence of a direct invasion of mastoid cortex or through external auditory canal (EAC) and middle ear.

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https://www.actaitalica.it/article/view/2647/1049

Affiliations

Luigi Lorini

Medical Oncology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

Michele Tomasoni

Otorhinolaryngology-Head and Neck Surgery Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

Paolo Rondi

Radiology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

Andrea Esposito

Medical Oncology Unit, Department of Medical & Surgical Specialties, Radiological Sciences & Public Health, University of Brescia, ASST Spedali Civili, 25123 Brescia, Italy

Marco Ravanelli

Radiology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

Alberto Schreiber

Otorhinolaryngology–Head and Neck Surgery Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

Antonio Biroli

Neurosurgery Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

Paolo Bossi

Medical Oncology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST Spedali Civili, Brescia, Italy

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Copyright

© Società Italiana di Otorinolaringoiatria e chirurgia cervico facciale , 2023

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