Feasibility of flow cytometry in the rhinologist’s clinic
Dear Editor,The assessment of the inflammatory pattern in patientswith rhinitis is conventionally performed by nasal cytology1. However, some studies have investigated nasal inflammationby flow cytometry, even though most aimedat evaluating issues far from conventional rhinology 2-8.Flow cytometry allows to define a series of additionalaspects in comparison with traditional nasal cytology,including cellular volume and density, the antigenic andgenetic cellular pattern, and the functional state, such asactivation. Moreover, flow cytometry is automated andwell standardised, so it may be considered as a preciseand accurate method to analyse the cellular pattern in nasalinflammation. On the contrary, it is usually consideredexpensive and laborious, as requires adequate machineryand well-trained staff.The current experience was determined to evaluate the feasibilityof performing flow cytometry in the rhinologist’sclinic. For this purpose, we chose a real-world model suchas a clinical setting: 41 consecutive patients (23 males, 18females, mean age 38.7 years) were visited at a rhinologyclinic in two consecutive days and enrolled. All hadnasal complaints that need thorough otorhinolaryngologicalevaluation. Patients were visited, and nasal scraping, endoscopy and lavage were carried out.